SERUM CORTISOL, PROGESTERONE AND TOTAL ANTIOXIDANT STATUS OF STUDENTS PRE- AND POSTEXAMINATION

Author: Awalu Chimezie Joseph
Department: Medical Laboratory
Affiliation: Nnamdi Azikiwe University Awka

Stress is defined as a mental or emotional strain resulting from very demanding circumstances. In recent years, traumatic episode and poor results following school examination have made stress an issue of major concern in academics. This study aimed to investigate examination induced stress among apparently healthy University students in relation to some biochemical parameters and antioxidants status pre- and post-examination. This is a case controlled study involving 40 examinees as test group and 40 non-examinees as control group. Serum concentrations of cortisol and progesterone were estimated by ELISA method, and total antioxidants status (TAS) was quantified by colorimetric method. Data obtained were subjected to statistical analysis using SPSS software application (version 16.0) and the results expressed as mean ± standard deviation. The results of the pre and post examination showed a significant decrease in cortisol (from 34.84±8.50 to 21.18±14.53) while progesterone levels significantly increased from 0.42±0.32 to 0.92±0.96 (p 0.05). The mean serum cortisol in subjects with outstanding academic activity was not statistically significant when compared to subjects without outstanding academic activity (p>0.05). In conclusion, the differences in the biochemical parameters observed in this study pre and post examination suggest that examination has the tendency to induce stress which could culminate to oxidative damage in chronic cases.

For full copy of this document please visit the digital library help desk.

Tags: , , , , , , , , , ,

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s


%d bloggers like this: